New version of SAFE GUI is available for download. SAFEGUI provides a user-friendly graphical interface for the assessment of categorical significance in microarray studies, while properly accounting for the effects of correlations among genes. SAFEGUI incorporates both permutation and more recently proposed bootstrap algorithms that are demonstrated to be more powerful in detecting differential expression across categories of genes.
Update:
Now you can save and load your SAFE projects simply by using File menu.
You can download here: SAFEGUI
Please read installation instructions before start.
SAFEGUI page